While raising three children and taking care of the household, Fanny Angelina Hesse supported, documented, and archived her husband’s work, creating stunning scientific illustrations of bacterial and fungal colonies. During the hot Summer of 1881, she watched as Hesse struggled with gelatine-based growth media. Fanny Angelina, recalling the stability of her agar-based desserts, suggested that they try that instead. Hesse wrote a letter to Koch informing him about the switch, and Koch mentioned agar for the first time in his 1882 groundbreaking paper on the discovery of the tuberculosis bacillus.
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老爸知道自己喊人抬牛的做法危险，他也怕再麻烦亲戚们，说自己记住了教训，以后会将牛犊拴起来。在农村，将一头牛拴住最保险的方式，是用一个铁环硬生生扎过牛的鼻孔，再套上连接槽边木桩的绳索，牛会因为怕疼，不敢摆脱缰绳逃跑。
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Photograph: Julian Chokkattu。关于这个话题，爱思助手下载最新版本提供了深入分析
Publication date: 10 March 2026